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Expression of THY-1 on rat T cells and its relevance as a maturation marker of T cells in rats

✍ Scribed by Katsuto Hozumi; Takashi Masuko; Yoshiyuki Hashimoto


Book ID
104179742
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
373 KB
Volume
39
Category
Article
ISSN
0165-2478

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A mutant strain of Long-Evans cinnamon (LEC) rats was found to have a novel defect in T-cell maturation, i.e., arrest of differentiation from CD4 + 8 + to CD4 + 8 -, but not to CD4 -8 + thymocytes. Despite the maturational arrest of CD4 + 8 -thymocytes, some CD4 + T cells occurred in peripheral lymp