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Expression of theRETProto-oncogene Is Regulated by TFAP2C in Breast Cancer Independent of the Estrogen Receptor

✍ Scribed by Spanheimer, Philip M.; Woodfield, George W.; Cyr, Anthony R.; Kulak, Mikhail V.; White-Baer, Lola S.; Bair, Thomas B.; Weigel, Ronald J.

Book ID
120433011
Publisher
Springer
Year
2012
Tongue
English
Weight
835 KB
Volume
20
Category
Article
ISSN
1068-9265

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Estrogen regulated expression of the p21
Estrogen regulated expression of the p21Waf1/Cip1 gene in estrogen receptor positive human breast cancer cells
✍ Soma Mandal; James R. Davie πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 183 KB

## Abstract The cyclin‐dependent kinase inhibitor protein p21^Waf1/Cip1^ is a potent tumor suppressor. Here, we demonstrate that estradiol regulates the p21^Waf1/Cip1^ gene. Estradiol induces p21^Waf1/Cip1^ mRNA expression within 30–60 min independent of new protein synthesis in the estrogen recept