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Expression of the Wnt antagonist DKK3 is frequently suppressed in sporadic epithelial ovarian cancer

✍ Scribed by An You; Emmanouil Fokas; Lin-Fang Wang; Haitao He; Beate Kleb; Dieter Niederacher; Rita Engenhart-Cabillic; Han-Xiang An


Book ID
106124375
Publisher
Springer-Verlag
Year
2010
Tongue
English
Weight
409 KB
Volume
137
Category
Article
ISSN
1432-1335

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Promoter methylation of the Wnt/Ξ²-cateni
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## Abstract ## BACKGROUND: Abnormal activation of the Wnt/β‐catenin signaling pathway is common and critical in the pathogenesis of digestive cancers. In this study, the authors investigated the promoter methylation of the dickkopf homolog 3 gene __Dkk‐3__ in these cancers and its prognostic signi