𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Expression of the multidrug resistance gene in leukemic cells

✍ Scribed by Shenwu Wang; Tao Bai; Xiaorong Liu; Fuxiang Shan; Bin Jiang; Shicheng Zhao

Book ID
112974459
Publisher
Chinese Anti-Cancer Association
Year
1993
Tongue
English
Weight
520 KB
Volume
5
Category
Article
ISSN
1000-9604

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The multidrug resistance phenotype (MDR) is one of the major causes of failure in cancer chemotherapy and it is associated with the over-expression of P-glycoprotein (P-gp or MDR1) in tumor cell membranes. A constitutive NF-kappaB activity has been observed in several haematological malignancies and