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Expression of the insulin-like growth factor (IGF) system and steroidogenic enzymes in canine testis tumors

✍ Scribed by Monique AJ Peters; Jan A Mol; Monique E van Wolferen; Marja A Oosterlaken-Dijksterhuis; Katja J Teerds; Frederik J van Sluijs

Book ID: 119903678
Publisher: BioMed Central
Year: 2003
Tongue: English
Weight: 285 KB
Volume: 1
Category: Article
ISSN: 1477-7827
DOI: 10.1186/1477-7827-1-22

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## Background and Objectives: We have previously shown that insulin-like growth factor (IGF)-responsive murine sarcomas demonstrate inhibition of local and metastatic disease growth when implanted in an IGF-deficient host animal. In this experiment, we tested whether IGF receptor (IGF-R) and ligan