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EXPRESSION OF THE IMMUNOGLOBULIN J CHAIN IN A MURINE B LYMPHOMA IS DRIVEN BY AUTOCRINE PRODUCTION OF INTERLEUKIN 2

✍ Scribed by Sarah L. Gaffen; Susan Wang; Marian E. Koshland


Book ID
115595920
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
274 KB
Volume
8
Category
Article
ISSN
1043-4666

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✍ Andrew C. Bakker; Leo A. B. Joosten; Onno J. Arntz; Monique M. A. Helsen; Alison πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 925 KB

Objective. To determine the efficacy of local human interleukin-1 receptor antagonist (HuIL-1Ra) gene therapy in murine collagen-induced arthritis (CIA). Methods. DBN1 mice were immunized against bovine type I1 collagen. Before the onset of arthritis, NIH/3T3 fibroblasts transfected with pMFG-IRAP