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Expression of the IL-10 receptor on human monocytes is moderately suppressed by glucocorticoids

✍ Scribed by Jeroen Visser; Lex Nagelkerken

Book ID: 117798065
Publisher: Elsevier Science
Year: 2002
Tongue: English
Weight: 104 KB
Volume: 2
Category: Article
ISSN: 1567-5769
DOI: 10.1016/s1567-5769(02)00113-3

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## Abstract In Th1 and Th2 memory lymphocytes, the genes for the cytokines interleukin (IL)‐4 and interferon‐γ (IFN‐γ) are imprinted for expression upon restimulation. This cytokine memory is based on expression of the transcription factors T‐bet for IFN‐γ, and GATA‐3 for IL‐4, and epigenetic modif