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Expression of the Human Gene Encoding Urokinase Plasminogen Activator Receptor Is Activated by Disruption of the Cytoskeleton

✍ Scribed by Ulvi Bayraktutan; Peter Jones


Book ID
118286843
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
916 KB
Volume
221
Category
Article
ISSN
0014-4827

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The ability of microglia to migrate through central nervous system (CNS) tissue requires proteolytic degradation of components of the extracellular matrix. Urokinase plasminogen activator (uPA), when bound to its cell surface receptor (uPAR), is an active cell surface protease. uPAR expression has b