Expression of the high molecular weight melanoma-associated antigen by percytes during antigionesis in tumors and in healing wounds

Suppression of human melanoma tumor grow

Suppression of human melanoma tumor growth in SCID mice by a human high molecular weight-melanoma associated antigen (HMW-MAA) specific monoclonal antibody

✍ Christine Hafner; Heimo Breiteneder; Soldano Ferrone; Christiane Thallinger; Ste 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 French ⚖ 199 KB

## Abstract The lack of efficacy of available therapies for the treatment of malignant melanoma has emphasized the need to develop novel therapeutic strategies to prevent melanoma growth. We have tested whether the anti‐HMW‐MAA mAb 225.28S is able to inhibit human melanoma tumor growth in SCID mice