Expression of the cyclin-dependent kinase inhibitor p27kip1 is reduced in gastric epithelial cells of patients with helicobacter pylori-induced gastritis
โ Scribed by Shirin, Haim; Kawabata, Yuichi; Hibshoosh, Hanina; Andrescu, Dorin; Bernard Weinstein, I.; Moss, Steven F.
- Book ID
- 121971655
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 184 KB
- Volume
- 118
- Category
- Article
- ISSN
- 0016-5085
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Reduced expression of the cyclin-dependent kinase inhibitor p27 Kip1 has been reported to correlate with poor survival in cohorts of breast and colorectal carcinoma patients. Posttranslational ubiquitin-mediated proteasomal proteolysis is related to p27 Kip1 protein levels. However, to the authors'
The p27 Kip1 protein is a negative regulator of the cell cycle and a potential tumor suppressor gene. Reduced expression of the p27 Kip1 protein has been reported in several human tumors and has been associated with higher tumor grade and increased mortality in breast, lung, colon, prostate, bladder