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Expression of the caspase-8 gene in neuroblastoma cells is regulated through an essential interferon-sensitive response element (ISRE)

✍ Scribed by Casciano, I; De Ambrosis, A; Croce, M; Pagnan, G; Di Vinci, A; Allemanni, G; Banelli, B; Ponzoni, M; Romani, M; Ferrini, S

Book ID
110016648
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
147 KB
Volume
11
Category
Article
ISSN
1350-9047

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An interferon-sensitive response element
An interferon-sensitive response element is involved in constitutive caspase-8 gene expression in neuroblastoma cells
✍ Alessandro De Ambrosis; Ida Casciano; Michela Croce; Gabriella Pagnan; Luana Rad 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 French ⚖ 625 KB

## Abstract We previously identified a 1.2 Kb DNA element (P‐1161/+16), 5′ to __caspase‐8__ exon‐1, that acts as promoter in caspase‐8‐positive, but not in caspase‐8‐negative neuroblastoma (NB) cells. The P‐1161/+16 DNA element regulates both constitutive and interferon IFN‐γ‐inducible caspase‐8 ex