Expression of the bcl-2 oncogene product and chromosomal translocation t(14; 18) in Hodgkin's disease
β Scribed by Johann Lorenzen; Martin-Leo Hansmann; Francesco Pezzella; Cristina Hesse; Michael Kneba; Kevin C. Gatter; Robert Fischer
- Book ID
- 119023991
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- English
- Weight
- 780 KB
- Volume
- 23
- Category
- Article
- ISSN
- 1532-8392
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The t(14;18)(q21;q34) BCL2 translocation is a common genetic alteration in follicular and diffuse large B-cell lymphoma. However, it is not invariably associated with BCL2 gene overexpression due to undefined mechanisms that regulate expression from the proximal immunoglobulin heavy-chain (IgH) prom
The c-kit proto-oncogen (CD117) has been described to be present in normal and neoplastic hemopoietic cells including both myeloid and lymphoid lineages. Among the normal lymphoid cells CD117 expression would be restricted to a small subset of NKcells, and to early T-cell precursors and it is not ex