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Expression of the ataxia-telangiectasia gene (ATM) product in human cerebellar neurons during development

✍ Scribed by Akira Oka; Sachio Takashima

Book ID
117476964
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
716 KB
Volume
252
Category
Article
ISSN
0304-3940

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The ATDC gene was originally identified by its ability to complement the radiosensitivity defect of an ataxia telangiectasia (AT) fibroblast cell line. Because hypersensitivity to ionizing radiation is an important feature of the AT phenotype, we reasoned that ATDC may function generally in the supp