Transforming growth factor f3 has a specific stimulatory effect on collagen formation by hepatic lipocytes, a cell type believed to be a major source of extracellular matrices in the liver. Because monocytes and macrophages are the known sources of transforming growth factor p, Kupffer cells-residen
✦ LIBER ✦
Expression of TGFβ1 by Rat Kupffer Cells: Implication for a Pathogenetic Role in Alcoholic Liver Fibrosis
✍ Scribed by MASAKI MATSUOKA; HIDEKAZU TSUKAMOTO
- Book ID
- 119863949
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 293 KB
- Volume
- 593
- Category
- Article
- ISSN
- 0890-6564
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Transforming growth factor-beta1 (TGF-beta1) is widely recognized for its multiple roles in development, cellular maintenance, and protection against injury. In the brain, TGF-beta1 upregulation in microglia/macrophages is a predominant response to lesion and during pathology. However, the precise f