The immunohistochemical expression of p53 and c-erbB-2 gene proteins was examined in a series of 130 breast adenocarcinomas. This study intended to investigate whether the frequency of the altered expression of the tumour suppressor gene p53 and the overexpression of the oncogene c-erbB-2 in breast
โฆ LIBER โฆ
Expression of Survivin, Mutant p53 and C-erbB-2 in Breast Cancer and Its Clinical Significance
โ Scribed by Huihua XIONG; Shiying YU; Shu XIA; Liang ZHUANG
- Publisher
- Springer
- Year
- 2005
- Tongue
- English
- Weight
- 113 KB
- Volume
- 4
- Category
- Article
- ISSN
- 1610-1979
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To document whether c-erbB-2 over-expression or p53 accumulation in tumour cells was predictive of response to chemo-or radiotherapy, we analyzed a population of patients with breast cancer assigned to neo-adjuvant therapy (median follow-up: 54 months). T2/T3-N0N1b-M0 tumours (329 cases) were treate