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Expression of Survivin Gene and Its Relationship with Clinical Multidrug Resistance in Osteosarcoma

✍ Scribed by Tao NIE; Min DAI; Shizhang ZONG


Book ID
106314394
Publisher
Springer
Year
2005
Tongue
English
Weight
98 KB
Volume
4
Category
Article
ISSN
1610-1979

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Expression of the multidrug resistance g
✍ Jay S. Wunder; Robert S. Bell; Lester Wold; Dr. Irene L. Andrulis πŸ“‚ Article πŸ“… 1993 πŸ› Elsevier Science 🌐 English βš– 717 KB

## Abstract Resistance to combination chemotherapy remains a challenge in the treatment of osteosarcoma yet has not been studied extensively in this tumour. One mechanism of multiple drug resistance is increased expression of the multidrug resistance gene (mdr1). The level of mdr1 messenger RNA (mR