Expression of SR-BI (Scavenger Receptor Class B Type I) in turtle (Chrysemys picta) tissues and other nonmammalian vertebrates

✍ Scribed by Duggan, Annemarie E. ;Marie, Ronald Ste. ;Callard, Ian P.

• Publisher: John Wiley and Sons
• Year: 2002
• Tongue: English
• Weight: 144 KB
• Volume: 292
• Category: Article
• ISSN: 0022-104X
• DOI: 10.1002/jez.10067

✦ Synopsis

Abstract

In this study, the tissue distribution of the expression of an HDL‐receptor (SR‐BI; Scavenger Receptor Class B Type I) was investigated in the turtle using an antiserum to murine SR‐BI. Several turtle tissues including liver, heart, small intestine, kidney, oviduct, ovary, and testis were shown to express an 82 kDa membrane protein. In addition, SR‐BI expression in livers of other nonmammalian species such as the chicken, frog, goldfish, shark, and skate is also reported. Ovarian SR‐BI expression varies seasonally in the turtle as do plasma levels of apoA‐I and cholesterol ester. It is possible that changing levels of SR‐BI, the receptor for apoA‐I, is physiologically relevant to the demands of the turtle ovarian cycle and cholesterol distribution. J. Exp. Zool. 292:430–434, 2002. © 2002 Wiley‐Liss, Inc.