Expression of some neurotrophins in the spinal motoneurons after cord hemisection in adult rats
โ Scribed by Dan Xia Qin; Xiao li Zou; Wei Luo; Wei Zhang; Hong Tian Zhang; Xiao Li Li; Han Zhang; Xu Yang Wang; Ting-Hua Wang
- Book ID
- 116769127
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 667 KB
- Volume
- 410
- Category
- Article
- ISSN
- 0304-3940
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Expression of the neurotrophins NT-4, brain-derived neurotrophic factor (BDNF), and NT-3 in adult rat lumbosacral spinal cord motoneurons is reported. A sensitive in situ hybridization procedure demonstrates localization of the mRNA for each of these neurotrophins within spinal motoneurons of the ad
Potential roles of trophins in the normal and injured spinal cord are largely undefined. However, a number of recent studies suggest that adult spinal cord expresses neurotrophin receptors and responds to the neurotrophins, brain-derived neurotrophic factor (BDNF) and neurotrophin 3 (NT3), particula