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Expression of small-conductance calcium-activated potassium channels (SK3) in skeletal muscle: regulation by muscle activity

โœ Scribed by Morgana Favero; De-Jian Jiang; Christian Chiamulera; Alberto Cangiano; Guido Francesco Fumagalli


Book ID
110116242
Publisher
Cambridge University Press
Year
2008
Tongue
English
Weight
632 KB
Volume
586
Category
Article
ISSN
0022-3751

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Skeletal muscle becomes hyperexcitable following denervation and when cultured in the absence of nerve cells. In these circumstances, the bee venom peptide toxin apamin, a blocker of small-conductance calcium-activated potassium (SK) channels, dramatically reduces the hyperexcitability. In this repo