Expression of Recombinant Human Soluble Type II Transforming Growth Factor-β Receptor inPichia pastorisandEscherichia coli:Two Powerful Systems to Express a Potent Inhibitor of Transforming Growth Factor-β
✍ Scribed by Harrie L. Glansbeek; Henk M. van Beuningen; Elly L. Vitters; Peter M. van der Kraan; Wim B. van den Berg
- Book ID
- 115645252
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 209 KB
- Volume
- 12
- Category
- Article
- ISSN
- 1046-5928
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Retinoblastoma cells are resistant to transforming growth factor-b (TGF-b) activity due to the absence of TGF-b binding. To further elucidate the mechanism of TGF-b resistance, we studied the expression of the TGF-b receptors and SMADs by using the Y79 and WERI-Rb-1 retinoblastoma cell lines. Bindin
lmmunohistochemical studies of transforming growth factor$ (TGF-P) and its receptors have been carried out on 16 glioma tissues and compared with 5 cases of gliosis. Significantly higher expressions of TGF-PI, as well as type-I and type4 TGF-fl receptors (TpR-I and TPR-II, respectively), were observ