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Expression of pyrimidine nucleoside phosphorylase mRNA plays an important role in the prognosis of patients with oesophageal cancer

โœ Scribed by Yamagata, M; Mori, M; Mimori, K; Mafune, K-I; Tanaka, Y; Ueo, H; Akiyoshi, T


Book ID
110000956
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
78 KB
Volume
79
Category
Article
ISSN
0007-0920

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Expression of the muscle glycogen phosph
โœ Gisela Nogales-Gadea; Juan Carlos Rubio; Israel Fernandez-Cadenas; Ines Garcia-C ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 194 KB

Nearly 35% of all mutations identified in the muscle glycogen phosphorylase gene (PYGM) in patients with McArdle disease result in premature termination codons (PTCs), particularly the p.R50X mutation. The latter accounts for more than 50% of the mutated alleles in most Caucasian patient populations