Expression of prolactin receptors in rat reproductive tissues during periovulatory prolactin imbalance
β Scribed by R. L. Bogorad; T. Kotok; A. N. Smirnov; V. M. Turovetskii; O. V. Smirnova
- Publisher
- Springer US
- Year
- 2000
- Tongue
- English
- Weight
- 386 KB
- Volume
- 129
- Category
- Article
- ISSN
- 0007-4888
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Insulin and type I insulin-like growth factor (IGF-I) suppressed growth hormone (GH) expression followed by the induction of prolactin (PRL) biosynthesis in MtT/S cells cultured with normal sera. Insulin also increased the peptidylarginine deiminase activity in a dose-dependent manner. The increase
Prolactin has a variety of important physiological effects on peripheral tissue and on the brain. The behavioral effects of prolactin include the induction of maternal behavior and increased food intake. Prolactin acts via its cognate receptors which have two forms, a short and a long form. The long