Expression of pre-S1, pre-S2, S and X peptides in relation to viral replication in livers with chronic hepatitis B
β Scribed by KOYU SUZUKI; TOSHIKAZU UCHIDA; TOSHIO SHIKATA; MITSUHIKO MORIYAMA; YASUYUKI ARAKAWA; MASASHI MIZOKAMI; FUSAAKI MIMA
- Book ID
- 114796717
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 870 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0106-9543
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To determine the time sequence of expression of pre-S2 peptide (1 2C150) during the presymptomatic phase of acute hepatitis B, we used a monoclonal antibody radioimmunoassay in five subjects followed from 30 to 70 days before the onset of liver damage. Pre-S2 peptide was present in serum at low leve
## Abstract Frozen cryostat sections and sera from 30 patients with chronic delta infection were examined for preβS1 and preβS2 geneβencoded proteins, and the results were compared to markers in liver and serum HBV and HDV replication. PreβS1 and preβS2 were detected by indirect immunofluorescence