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Expression of platelet-derived growth factor and activated receptor in clinical specimens of epithelial ovarian cancer and ovarian carcinoma cell lines

✍ Scribed by Sachin M Apte; Corazon D Bucana; Jerald J Killion; David M Gershenson; Isaiah J Fidler


Book ID
113959162
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
559 KB
Volume
93
Category
Article
ISSN
0090-8258

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## Abstract ## BACKGROUND Tyrosine kinases, such as c‐KIT, c‐ABL, and platelet‐derived growth factor‐beta (PDGFR‐β), are important regulators of cell growth. Highly potent and selective inhibitors of tyrosine kinases are being investigated as alternatives to standard chemotherapy. One such inhibit