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Expression of pAkt affects p53 codon 72 polymorphism-based prediction of response to radiotherapy in nasopharyngeal carcinoma

✍ Scribed by Xiaoxue Xie, Hui Wang, Hekun Jin, Shuyu Ouyang, Jumei Zhou, Jun Hu…


Book ID
120696429
Publisher
BioMed Central
Year
2013
Tongue
English
Weight
734 KB
Volume
8
Category
Article
ISSN
1748-717X

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## Abstract There are increasing reports showing the clinical significance of the __p53__ polymorphism status in terms of the response to chemotherapy. We investigated whether __p53__ polymorphism and mutation were associated with __in vitro__ sensitivity to 5‐fluorouracil (5‐FU) in patients with c