✦ LIBER ✦

Expression of p53-regulated genes in human cultured lymphoblastoid TSCE5 and WTK1 cell lines after spaceflight in a frozen state

✍ Scribed by A. Takahashi; H. Suzuki; K. Omori; M. Seki; T. Hashizume; T. Shimazu; N. Ishioka; T. Ohnishi

Book ID: 108068319
Publisher: Elsevier Science
Year: 2011
Tongue: English
Weight: 157 KB
Volume: 47
Category: Article
ISSN: 0273-1177
DOI: 10.1016/j.asr.2010.11.002

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Mutation in p53 and de-regulation of p53

Mutation in p53 and de-regulation of p53-related gene expression in three human cell lines immortalized with 4-nitroquinoline 1-oxide or 60Co gamma rays

✍ Mikio Itjima; Koichiro Mihara; Tadashi Kondo; Toshiya Tsuji; Chikashi Ishioka; M 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 French ⚖ 739 KB

IMMORTALIZED In vitro models of malignant transformation of human cells may provide considerable insight into the mechanisms of multistep carcinogenesis. It is well established that normal human cells must be immortalized before they can be malignantly transformed; however, they are stringently dest

Decreased cytotoxic effects of doxorubic

Decreased cytotoxic effects of doxorubicin in a human ovarian cancer-cell line expressing wild-type p53 and WAF1/CIP1 genes

✍ Faina Vikhanskaya; Maurizio D'Incalcimassimo Broggini 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 French ⚖ 936 KB

The cytotoxicity of Doxorubicin and cis-dichloro-diammineplatinum (DDP) was evaluated in clones, obtained from a human ovarian cancer cell line transfected with a ternperaturesensitive p53 mutant, which express mutant p53 at 37°C and wild-type-like p53 at 32°C. DDP was equally active in cells not ex