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Expression of p27(Kip1), cyclin D3 and Ki67 in BPH, prostate cancer and hormone-treated prostate cancer cells

✍ Scribed by David Nikoleishvili; Ambrosi Pertia; Omar Trsintsadze; Nino Gogokhia; Laurent Managadze; Archil Chkhotua


Publisher
Springer Netherlands
Year
2008
Tongue
English
Weight
398 KB
Volume
40
Category
Article
ISSN
0301-1623

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## Abstract The vitamin D receptor (VDR) is a member of the steroid/retinoid receptor superfamily of nuclear receptors and has potential tumor‐suppressive functions in prostate and other cancer types. Vitamin D~3~ (VD~3~) exerts its biological actions by binding within cells to VDR. The VDR then in