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Expression of murine killer immunoglobulin-like receptor KIRL1 on CD1d-independent NK1.1+T cells

✍ Scribed by Erica B. Wilson; Christine A. Parachoniak; Carmine Carpenito; Dixie L. Mager; Fumio Takei


Book ID
105947841
Publisher
Springer-Verlag
Year
2007
Tongue
English
Weight
470 KB
Volume
59
Category
Article
ISSN
0093-7711

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The pan-NK cell marker NK1.1, present in some mouse strains, is also found on a subset of TCRalphabeta+ lymphocytes termed NKT cells. These cells are primarily CD4+ or CD4-CD8- (double negative, DN), and both NKT subpopulations contain cells reactive with the MHC class I-like molecule CD1d. Murine N