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Expression of multidrug resistance 1 and glutathione-S-transferase-[Pi ] protein in nasopharyngeal carcinoma

✍ Scribed by Chi-Long Chen; Tzung-Shiahn Sheen; Ia-Uen Lou; Ai-Chun Huang

Book ID
117818513
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
179 KB
Volume
32
Category
Article
ISSN
1532-8392

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While P-glycoprotein (Pgp) and multidrug resistance-associated protein 1 (MRP1) are known to be important in acquired doxorubicin resistance, the role of glutathione S-transferases (GST) remains unclear. Our study assessed roles of these 3 factors in a human drug-sensitive carcinoma cell line (HEp2)