Expression of MUC1, Thomsen-Friedenreich antigen, Tn, sialosyl-Tn, and α2,6-linked sialic acid in hepatocellular carcinomas and preneoplastic hepatocellular lesions

Colon carcinoma glycoproteins carrying α

Colon carcinoma glycoproteins carrying α 2,6-linked sialic acid reactive with Sambucus Nigra agglutinin are not constitutively expressed in normal human colon mucosa and are distinct from sialyl-tn antigen

✍ Toshihiko Murayama; Christian Zuber; Walter K.F. Seelentag; Wei-Ping Li; Wolfgan 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 French ⚖ 429 KB

In human colon carcinoma, increased amounts of sialic acids have been found and correlated with tumor progression. Further, the degree of O-acetylation of sialic acid residues in normal mucosa is higher than in colon carcinoma. Thus, tumor-associated sialylated antigens may be constitutively express