Germline transcription of the Tcrb-V8.2 gene has been recently shown to occur in a lymphoid precursor cell line and to result in weak expression of an aberrant T-cell receptor (Tcr) ~ chain on the cell surface. An investigation into the expression of a similar Tcr structure in normal lymphoid sites
Expression of mouse and frog rRNA genes: transcription and processing
β Scribed by Barbara Sollner-Webb; Louise Pape; Kenneth Ryan; Edward B. Mougey; Regina Poretta; Emil Nikolov; Mark H. Paalman; Inara Lazdins; Cathy Martin
- Publisher
- Springer
- Year
- 1991
- Tongue
- English
- Weight
- 513 KB
- Volume
- 104
- Category
- Article
- ISSN
- 0300-8177
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β¦ Synopsis
This article summarizes a number of lines of investigation of rRNA gene expression that are ongoing in the laboratory. These studies focus on mouse and frog, two distant vertebrate species. One major conclusion is that the basic properties of rRNA gene expression appear remarkably well conserved in evolution, with only relatively minor perturbations between frog and mouse, contrary to the common interpretation of the species-selectively between mouse and human rDNA transcription (e.g., 1). This is true both for the process of rDNA transcription and for the subsequent rRNA processing event.
π SIMILAR VOLUMES
The transcription and RNA processing signals of the rRNA operons (rrnA and rrnB) of Mycoplasma capricolum were analyzed by mapping the 5' ends of in vivo and in vitro synthesized RNAs. The results of both in vitro and in vivo analyses point to the rrnA operon being transcribed from two promoters (P1