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Expression of MMP-2, MMP-9, and Urokinase-Type Plasminogen Activator in Cervical Intraepithelial Neoplasia

✍ Scribed by Jae Hong No; Hoenil Jo; Su-Hyeong Kim; In-Ae Park; Daehee Kang; Chae Hyeong Lee; Seung-Su Han; Jae Weon Kim; Noh-Hyun Park; Soon-Beom Kang; Yong-Sang Song


Book ID
111399301
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
201 KB
Volume
1171
Category
Article
ISSN
0890-6564

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Enhanced expression of the type IV collagenases MMP-2 and MMP-9, or lack of their inhibitors TIMP-1 and TIMP-2, has been associated with tumour invasion and metastatic potential in several experimental models. Regulation of enzyme activity is clearly a key step in tumour invasion, and recently a pot