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Expression of metallothionein-I and II in skin ageing and its association with skin proliferation

โœ Scribed by C. Ma; L.-F. Li; X. Chen

Book ID
108671527
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
253 KB
Volume
164
Category
Article
ISSN
0007-0963

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A single topical application of 12-O-tetradecanoylphorbol-13-acetate (TPA) was found to induce mRNA of a metallothionein (MT) gene or genes in the skin of Sencar mice, and papillomas produced by repeated applications of TPA were shown to have elevated levels of MT mRNA. Induction of MT mRNA was maxi