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Expression of metabotropic glutamate receptors in human melanocytes

โœ Scribed by G. Fisiehdla; C. Marehese; A. Copani; V. Bruno; G. Casabona; C. Frati; F. Nicoleiti

Book ID
116037941
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
130 KB
Volume
35
Category
Article
ISSN
0028-3908

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Cultured human melanocytes express mGlu5 metabotropic glutamate (mGlu) receptors, as shown by RT-PCR, immunocytochemistry, Western blot analysis, and measurement of agonist-stimulated polyphosphoinositide hydrolysis. The mGlu5 receptor agonists (S)-3,5-dihydroxyphenylglycine and quisqualate increase