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Expression of members of Wnt and Frizzled gene families in the postnatal rat cochlea

✍ Scribed by Nicolas Daudet; Chantal Ripoll; Jean-Pierre Molès; Guy Rebillard


Book ID
117385976
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
347 KB
Volume
105
Category
Article
ISSN
0169-328X

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The Wnt signaling pathway is essential for a wide array of developmental and physiological processes. Wnts are extracellular ligands that bind to frizzled (Fz) receptors at the membrane, canonically inducing ␤-catenin nuclear translocation and activation. Although ␤-catenin has been shown to be crit