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Expression of Mcl-1 in cerebellar granule neurons is regulated by IGF-I in a developmentally specific fashion

✍ Scribed by Jihui Zhang; A. Joseph D'Ercole

Book ID: 113567074
Publisher: Elsevier Science
Year: 2004
Tongue: English
Weight: 337 KB
Volume: 152
Category: Article
ISSN: 0165-3806
DOI: 10.1016/j.devbrainres.2004.07.008

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## Abstract The aim of the present study was to evaluate the neuroprotective effects of caffeine, an inhibitor of ataxia telangiectasia mutated (ATM) enzyme and an antagonist of adenosine receptors, in two models of apoptosis in cerebellar granule neurons (CGNs): the inhibition of mitochondrial com