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Expression of matrix metalloproteinases (MMPs) in peptic ulcers and in inflammatory bowel disease

โœ Scribed by P Puolakkainen; M-L Karjalainen-Lindsberg; M Vaalamo; T Airola; E Kivilaakso; U Saarialho-Kere


Book ID
118879465
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
179 KB
Volume
108
Category
Article
ISSN
0016-5085

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Matrix metalloproteinases (MMPs) are a family of Zn(2+)-dependent extracellular matrix (ECM) degrading endopeptidases that share common functional domains, activation mechanisms, and collectively have the capacity to degrade all types of ECM proteins. In addition to playing a central role in ECM tur

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## Background: The epidemiology of peptic ulcer and inflammatory bowel disease shows many similar patterns. The aim of the present study was to compare the geographic distribution of mortality from peptic ulcer with that from inflammatory bowel disease. Methods: Mortality data from 27 countries be