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Expression of matrix metalloproteinase (MMP)-7 and MMP-13 and loss of MMP-19 and p16 are associated with malignant progression in chronic wounds

✍ Scribed by U. Impola; L. Jeskanen; L. Ravanti; S. Syrjänen; B. Baldursson; V-M. Kähäri; U. Saarialho-Kere


Book ID
108668020
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
906 KB
Volume
152
Category
Article
ISSN
0007-0963

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✍ Nor Eddine Sounni; Eugenia N. Baramova; Carine Munaut; Erik Maquoi; Francis Fran 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 French ⚖ 778 KB

## Abstract Membrane‐type metalloproteinase‐1 (MT1‐MMP) is a transmembrane metalloproteinase overexpressed in tumors, which plays a major role in the first step of pro‐MMP‐2 activation, leading to the generation of an intermediate 62 kDa species. The second step of MMP‐2 activation that yields to t