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Expression of Matrix Metalloproteinase (MMP)-2 and MMP-9 in Breast Cancer with a Special Reference to Activator Protein-2, HER2, and Prognosis

✍ Scribed by Pellikainen, J. M.


Book ID
127171651
Publisher
American Association for Cancer Research
Year
2004
Tongue
English
Weight
167 KB
Volume
10
Category
Article
ISSN
1078-0432

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Enhanced expression of the type IV collagenases MMP-2 and MMP-9, or lack of their inhibitors TIMP-1 and TIMP-2, has been associated with tumour invasion and metastatic potential in several experimental models. Regulation of enzyme activity is clearly a key step in tumour invasion, and recently a pot