Decreased P-glycoprotein (P-gp/MDR1) exp
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Hans Blokzijl; Sara Vander Borght; Lisette I.H. Bok; Louis Libbrecht; Mariska Ge
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Article
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2007
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John Wiley and Sons
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English
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Background: Altered P-glycoprotein expression (P-gp/MDR1) and/or function may contribute to the pathogenesis of gastrointestinal inflammatory disorders. Low intestinal mRNA levels of the pregnane X receptor (PXR) have been linked to low MDR1 mRNA levels in patients with ulcerative colitis (UC). Here