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Expression of leptin and its long-form receptor in the marginal cutaneous tissues of diabetic foot ulcers

โœ Scribed by Cao, Ying; Gao, Fang; Li, Chen-Zhong; Xue, Yao-ming


Book ID
115516751
Publisher
Springer
Year
2012
Tongue
English
Weight
921 KB
Volume
49
Category
Article
ISSN
0940-5429

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The adipocyte secreted hormone leptin (OB) and its receptor (OB-R) are key regulators of mammalian body weight homeostasis. Two predominant isoforms of OB-R have been described: long form (OB-R L ) characterized as a signal transducing receptor that is highly expressed in specific nuclei of the hypo