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Expression of LAZ3/BCL6 in follicular center (FC) B cells of reactive lymph nodes and FC-derived non-Hodgkin lymphomas

✍ Scribed by Bajalica-Lagercrantz, S; Piehl, F; Lagercrantz, J; Lindahl, J; Weber, G; Kerckeart, J P; Porwit-MacDonald, A; Nordenskjöld, M

Book ID
110053435
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
214 KB
Volume
11
Category
Article
ISSN
0887-6924

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Nonrandom fusion of L-Plastin(LCP1) and LAZ3(BCL6) genes by t(3;13)(q27;q14) chromosome translocation in two cases of B-cell non-Hodgkin lymphoma
✍ Sylvie Galiègue-Zouitina; Sabine Quief; Marie-Paule Hildebrand; Claude Denis; La 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 194 KB 👁 1 views

The LAZ3(BCL6) gene on chromosome band 3q27 is nonrandomly disrupted in B-cell non-Hodgkin lymphoma (B-NHL) by chromosomal translocations clustered within a 3.3-kb MTC (major translocation cluster) located between the two first noncoding exons. These translocations generally result in the expression