✦ LIBER ✦

Expression of L3T4 molecules on Lyt-2+, class II-restricted antigen-specific T suppressor lymphocytes

✍ Scribed by Joachim Heuer; Joachim Degwert; Eckehart Kölsch

Book ID: 104755026
Publisher: Springer-Verlag
Year: 1986
Tongue: English
Weight: 698 KB
Volume: 24
Category: Article
ISSN: 0093-7711
DOI: 10.1007/bf00395537

No coin nor oath required. For personal study only.

✦ Synopsis

Three bovine serum albumin-specific Lyt-2 + T suppressor (Ts) cell clones from CBA/J mice have been analyzed with regard to expression of L3T4 molecules. All three Ts-cell clones can be stained with monoclonal antibodies (mAb) to L3T4. Tested for the two clones restricted to recognition of E k determinants, antigen-specific proliferation on antigen-presenting cells, but not the proliferation induced by conditioned medium can be inhibited by L3T4-specific mAb. In a similar way, Ts-cell cytolytic effector functions can be blocked by L3T4specific mAb. Thus L3T4 structures seem to play a role in Ts-cell functions. Furthermore, the data support the view that L3T4 expression can be a property of class Hrestricted T cells irrespective of their Lyt phenotype.

📜 SIMILAR VOLUMES

Stable expression of Lyt-2 homodimers on

Stable expression of Lyt-2 homodimers on L3T4+T cell clones

✍ Pauline F. Gallagher; Barbara Fazekas de St. Groth; Jacques F. A. P. Miller 📂 Article 📅 1986 🏛 John Wiley and Sons 🌐 English ⚖ 632 KB

Class-II HLA Restriction of Antigen-Spec

Class-II HLA Restriction of Antigen-Specific Human T-Lymphocyte Clones : Evidence of Restriction Elements on both DR and MT Molecules

✍ E. QVIGSTAD; E. THORSBY 📂 Article 📅 1983 🏛 John Wiley and Sons 🌐 English ⚖ 517 KB

Specific lysis of Listeria monocytogenes

Specific lysis of Listeria monocytogenes-infected macrophages by class II-restricted L3T4+ T cells

✍ Stefan H. E. Kaufmann; Erika Hug; Ulla Väth; Gennaro De Libero 📂 Article 📅 1987 🏛 John Wiley and Sons 🌐 English ⚖ 973 KB

Mice were infected with the intracellular bacterium, Lisferia monocytogenes, and T cell clones from spleens, lymph nodes and peritoneal exudates were established. The capacity of L3T4', Lyt2-T-cell clones to specifically lyse L. monocytogenes-infected macrophages was analyzed. As a source of target

Effective activation of resting mouse T

Effective activation of resting mouse T lymphocytes by cross-linking submitogenic concentrations of the T cell antigen receptor with either Lyt-2 or L3T4

✍ Klaus Eichmann; Jan-Ingvar Jönsson; Ingrid Falk; Frank Emmrich 📂 Article 📅 1987 🏛 John Wiley and Sons 🌐 English ⚖ 915 KB

T-Cell Clones With L3T4-Positive or Lyt-

T-Cell Clones With L3T4-Positive or Lyt-2-Positive Phenotypes Responding to Mutant MHC Class II Antigen and Inducing Graft Versus Host Reaction.

✍ Watanabe, Hisami; Fujiwara, Michio; Mashiko, Tomoju; Ito, Masaaki 📂 Article 📅 1989 🏛 Nature Publishing Group 🌐 English ⚖ 837 KB

Class II-restricted IgG2ab-specific T ce

Class II-restricted IgG2ab-specific T cells recognize a signal-minus form of the V-CH3b antigen

✍ Elizabeth K. Bikoff 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 795 KB