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Expression of intracellular calcium-binding proteins in cultured skin fibroblasts from Alzheimer and normal aged donors

✍ Scribed by Ursula G Föhr; Gary E Gibson; Beth Tofel-Grehl; Beat W Schäfer; Claus W Heizmann

Book ID
116106141
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
861 KB
Volume
1223
Category
Article
ISSN
0167-4889

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## Abstract Proteins of approximately 10,000 daltons (presumably metallothionein) and greater than 75,000 daltons bound ^64^Cu when this metal was added to fibroblast lysates. Treatment with either 2‐mercaptoethanol or the disodium salt of ethylenediamine tetraacetic acid demonstrated that the high