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Expression of interleukin 6 (IL-6) correlates with oestrogen receptor in human breast carcinoma

✍ Scribed by Fontanini, G; Campani, D; Roncella, M; Cecchetti, D; Calvo, S; Toniolo, A; Basolo, F

Book ID
111717670
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
119 KB
Volume
80
Category
Article
ISSN
0007-0920

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BACKGROUND. Interleukin-6 (IL-6) is secreted by normal epithelial breast cells but not by oncogene-transformed cells. Interleukin-6 is able to inhibit growth of breast carcinoma cells in culture. Interleukin-6 exerts its activity via two receptor subunits, IL-6R and glycoprotein 130 (gp130). The exp