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Expression of interferon receptors in pancreatic cancer: Identification of a novel prognostic factor

✍ Scribed by Reza F. Saidi; Frances Williams; Boris Silberberg; Vijay K. Mittal; Stephen G. ReMine; Michael J. Jacobs

Book ID
113920301
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
272 KB
Volume
139
Category
Article
ISSN
0039-6060

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## Abstract The epidermal growth factor receptor (EGFR) has previously been detected in the nucleus of cancer cells and primary tumors. We have reported that EGFR translocates from the plasma membrane to the nucleus. Accumulation of nuclear EGFR is linked to increased DNA synthesis and proliferatio