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Expression of interferon receptor genes in the liver as a predictor of interferon response in patients with chronic hepatitis C virus infection

โœ Scribed by Morita, K.; Tanaka, K.; Saito, S.; Kitamura, T.; Kondo, M.; Sakaguchi, T.; Morimoto, M.; Kiba, T.; Numata, K.; Okazaki, H.; Sekihara, H.

Book ID
123153077
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
161 KB
Volume
114
Category
Article
ISSN
0016-5085

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Expression of interferon receptor genes
Expression of interferon receptor genes in the liver as a predictor of interferon response in patients with chronic hepatitis C
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Interferon (IFN) receptor mRNA expression patterns in the liver have been shown to correlate with the effectiveness of IFN therapy in patients with hepatitis C virus (HCV) infection. However, it is not clear to what extent this factor contributes to the short (primary)-and long (sustained)term resul

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Interferon (IFN) demonstrates antiviral activity by binding to receptors on the cell surface. Expression of the IFN receptor in hepatocytes may be directly associated with a hepatitis C virus (HCV) infection and the response to IFN therapy. A competitive PCR method was developed to measure IFN alpha