Expression of immunoglobulin genes in the avian embryo bone marrow revealed by retroviral transformation

Long-term expression of the human glucoc

Long-term expression of the human glucocerebrosidase gene in vivo after transplantation of bone-marrow-derived cells transformed with a lentivirus vector

✍ Eun Young Kim; Young Bin Hong; Zhennan Lai; Youl-Hee Cho; Roscoe O. Brady; Sung- 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 249 KB

## Abstract ## Background Gaucher disease is a lysosomal storage disorder resulting from a deficiency of glucocerebrosidase (GC). Recently, lentivirus vectors have been developed for efficient gene transfer into hematopoietic stem cells (HSCs). A recombinant lentivirus vector was used to evaluate