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Expression of IL-23 and IL-17 and effect of IL-23 on IL-17 production in ankylosing spondylitis

✍ Scribed by Xinwei Wang; Zhiming Lin; Qiujing Wei; Yingjuan Jiang; Jieruo Gu

Publisher
Springer
Year
2009
Tongue
English
Weight
272 KB
Volume
29
Category
Article
ISSN
0172-8172

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## Abstract IL‐23 plays a critical role in the expansion of highly proinflammatory Th17 cells secreting IL‐17 and IL‐22. Recently, we demonstrated that Notch signaling drives IL‐22 secretion through the aryl hydrocarbon receptor (AHR) and plays a protective role in Con A‐induced hepatitis. In this