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Expression of IL-15RA or an IL-15/IL-15RA fusion on CD8+ T cells modifies adoptively transferred T-cell function in cis

โœ Scribed by Jesse Rowley; Archana Monie; Chien-Fu Hung; T.-C. Wu


Book ID
102824642
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
785 KB
Volume
39
Category
Article
ISSN
0014-2980

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## Abstract We determined the efficacy of __in vitro__ expanded P14 TCR transgenic CD8 T cells to mediate tumor cell elimination and to protect against viral infection in mice. Contrary to previous studies, an adoptive transfer model without lymphodepletion, vaccination or cytokine treatment was us